Nucleic Resources

Product Name: C6 MMT-Aminolinker Phosphoramidite
Nucleic Resources Catalogue Number: NR0002

M.W. : 589.76

Formula: C35H48N3O3P

Storage: Frozen, -10 to –20°C

Dilution (for 0.1M): 0.25g/4.2 ml
1.0g/17 ml

Structure:

Nucleic Resources C6 MMT aminolinker may be used to directly add a primary aliphatic (C6) amine group to the 5' end of an oligonucleotide. Using trityl-ON synthesis protocols, the MMT amine protecting group is retained after standard ammonium hydroxide cleavage and deprotection. When used with the trityl-ON protocol, this allows simple purification of the oligonucleotide by either RP cartridge or by RP HPLC.
The presence of a primary aliphatic amine group at the 5' terminus of an oligonucleotide allows the post-synthesis attachment of any number of amine reactive molecules.


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			Product Name: C6 MMT-Aminolinker Phosphoramidite Nucleic Resources Catalogue Number: NR0002 M.W. : 589.76 Formula: C35H48N3O3P Storage: Frozen, -10 to –20°C Dilution (for 0.1M): 0.25g/4.2 ml 1.0g/17 ml Structure: Nucleic Resources C6 MMT aminolinker may be used to directly add a primary aliphatic (C6) amine group to the 5' end of an oligonucleotide. Using trityl-ON synthesis protocols, the MMT amine protecting group is retained after standard ammonium hydroxide cleavage and deprotection. When used with the trityl-ON protocol, this allows simple purification of the oligonucleotide by either RP cartridge or by RP HPLC. The presence of a primary aliphatic amine group at the 5' terminus of an oligonucleotide allows the post-synthesis attachment of any number of amine reactive molecules.